Hormone Cream

Three Hormones Working Together

Hormones are the messengers of control in a vast network of organ-system commands in the body. The foundation of good health is based on balanced hormone levels.

Pregnenolone is the first steroid hormone produced from cholesterol and sits in the key position to be made into any of the other steroid hormones, such as DHEA, progesterone, the estrogens (three types: estrone, estradiol, estriol), testosterone, the corticosteroids and aldosterone. Pregnenolone can be converted into ANY of these hormones. Without a sufficient amount of pregnenolone, these hormone pathways will suffer—with insufficient amounts of certain hormones being made, and possibly with relative excesses of others. Pregnenolone is a direct precursor to DHEA and may enhance DHEA’s activity.

Progesterone, in addition to its own special hormonal effects, is a main player in the biosynthesis of many important hormones. Progesterone is a “precursor” hormone. This means that if the body has enough progesterone, it can be converted, as needed, into other steroid hormones, such as adrenal corticosteroids, estrogen and testosterone.

For example, if your estrogen levels were too low, the body could convert some of the progesterone derived from a natural progesterone cream into the type of estrogen needed. DHEA, a natural hormone secreted by the adrenal glands, is being touted as the fabled “fountain of youth.” Over 2,500 published research papers document the healthful benefits of DHEA.

A recent report concluded that DHEA “will improve the quality of life over a longer period and will postpone some of the unpleasant effects of aging, such as fatigue and muscle weakness.”

Facial Rejuvenation

Pregnenolone, progesterone and DHEA are all hormones which contain facial rejuvenation properties. Pregnenolone is an important hormone for the skin. Many people have reported that their facial skin that had loosened with aging, suddenly contracted back to a snugger, more elastic fit after taking small amounts of pregnenolone. Research
has shown that fiber cells, which are a major component of skin, contain the same contractile materials contained by muscles. Pregnenolone may allow skin cells to contract, restoring firmness to slack skin. Pregnenolone has been able to quickly cause other rapid anatomical changes which may stem from eliminating edema (water retention), seen in helping protruding eyes (as in Graves’ disease) to recede, helping joint cartilage to function normally without pain, or causing lungs to oxygenate the blood more efficiently in people
with emphysema.

If progesterone is low, especially if estrogen is dominant in relation to progesterone, then the roller coaster of difficult symptoms may begin. Skin is one part of the body affected. Low progesterone can lead to thinning of the skin as well as dry, wrinkly skin. Adequate amounts of progesterone can reverse this process.

Stress, Fatigue And Depression

Daily stress is now a fact of life. Unrelenting levels of multiple stressors, such as physical, environmental, mental or emotional factors, cause the adrenal glands to produce an abundance of chemicals, called gluco- corticoids (our “fight or flight” hormones), which are harmful when elevated for long periods of time.

When first subjected to stress, the adrenals produce these chemicals in excess (to help quickly alleviate the stressful situation). But as the stress continues, the exhausted adrenals cannot continue to hypersecrete, going into a state of insufficiency and eventually progressing to adrenal failure or “adrenal burnout.” This stress can take a toll on the body and can lead to a haggard, worn out appearance.

Because pregnenolone can be converted to other hormones, research shows that it can help greatly improve our resistance to stress and adrenal exhaustion—often at the core of aging and chronic disease. Pregnenolone can be converted into badly needed adrenal hormones which are often low due to stress and fatigue.

Pregnenolone was used in a study of Army pilots to study the effects of fatigue. By simply taking oral pregnenolone, the pilots showed dramatic decreases in fatigue, even under exhausting conditions.

Other studies show that pregnenolone functions as a neurohormone in the body. It has been shown to significantly help in balancing moods and emotions, such as depression, anxiety and irritability. Many women in the world today have an excess amount of estrogen and insufficient amounts of progesterone. This can lead to feelings of exhaustion, waking up tired, headaches and depression, taking a toll on the appearance of the skin.

Getting sufficient amounts of progesterone in the body may alleviate these symptoms and give the skin a youthful appearance again.

One of DHEA’s greatest contributions appears to be its ability to alleviate stress and the ravages of excess glucocorticoids produced by continually flogged adrenals.

In the initial stages of adrenal dysregulation, one may experience highly varied symptoms such as: food sensitivities, insomnia, immune deficiencies, debilitating fatigue, depression, PMS, menopause symptoms, blood sugar regulation problems (such as diabetes or hypoglycemia) and behavior disorders (such as hyperactivity or Attention Deficit Disorder). The later stages of “adrenal burnout” lead to chronic degenerative diseases. Adrenal dysregulation is at the core of many of these diseases.

References

Brown, E. and Walker, L., Menopause and Estrogen: Natural Alternative To Hormone Replacement Therapy, Frog, Ltd., Berkeley, CA, 1996.

Guth, L., et. Al., Key role of pregnenolone in combination therapy that promotes recovery after spinal cord injury, Proceedings Nat Acad Sci of USA, 91 (25):12308-12, 1994.

Laux, M. and Conrad, C. Natural Woman, Natural Menopause, Harper Collins Pub.: New York, NY, 1998.

Lee, John, What Your Doctor May Not Tell You About Menopause: The Breakthrough Book on Natural Progesterone, Warner Books: New York, 1996.

Ley, B., DHEA: Unlocking the Secrets of the Fountain of Youth, BL Publication, Newport Beach, CA, 1996.

Martin, R., The Estrogen Alternative, Healing Arts Press: Rochester, VT, 1998.

McGavack, T. et al., “The use of pregnenolone in various clinical disorders,” J Clin Endocrinol 11:559-77, 1951.

Pascal, A., DHEA—The Fountain of Youth Discovered? Exploring the Link Between Youth and Aging, Van der
Kar Press, Malibu, CA, 1996.

Pincus, G. et al., “Effects of administered pregnenolone on fatiguing psychomotor performance.” J Aviation Med 15:98-115, 1994.

Sahelain, Ray, Pregnenolone: Nature’s Feel Good Hormone, Avery Publishing Group, Garden City Park, NY, 1997.

Sahlian, F., DHEA: A Practical Guide, Be Happier Press, Marina Del Rey, CA, 1996.

Yen, SS, Morales, AJ, Nolan Nelson, JC. “Effects of replacement of dose of DHEA in men and women of
advancing age.” J Clin Endocrinol Metab 1994 Jun; 78(6):1360-7.